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Showing posts with the label Eisenberg

New developments. Exciting developments in the field of protein-lipid interactions.

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History The fluid mosaic model is one of the most powerful models depicting a biomembrane and the way how lipids are organized in a bilayer and the way proteins are inserted in or bound to such a bilayer of lipids [1]. Recent developments in this area are nicely reviewed elsewhere [2]. The notion that lipids serve more functions than simple creating a barrier in cells is nicely described in a classic but still relevant review by Dowhan [3]. Basically, the title: “Molecular basis for membrane phospholipid diversity: why are there so many lipids?” says it all. Protein-lipid interactions Numerous processes in biology have been recognized where protein-lipid interactions play a role [4-6]. Please be aware that this only serves as a small impression since this rapidly evolving field produces interesting new papers constantly. Tools to investigate protein-lipid interactions An interesting prediction method has been published that could serve as a tool to create so-called Eisenberg plots [7]....

Use of bioinformatics

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Use of bioinformatics in education   Here another piece I posted on ResearchGate which I think is worthwhile reading  https://www.researchgate.net/publication/339311520_Possible_examples_of_using_Bioinformatics_in_your_chemistry_or_biology_class In this concept I described possible examples of bioinformatics which can be used at secondary school/college level. This piece can serve as inspiration. I strongly believe that using bioinformatics will help students in getting a deeper understanding of rather abstract concepts like amino acids, peptides, proteins, secondary structure . The role of hydrophobicity in folding and binding mechanisms (and how 'we' all know this) becomes more understandable for students at this (undergraduate) level. I asked ChatGPT about this topic and this is what I got back: Bioinformatics is a powerful tool that can enhance the understanding of abstract biochemical concepts in both chemistry and biology classes. Here are some possible examples of...